PIHKAL: A Chemical Love Story

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Papaseit, E., Farré, M., Pérez-Mañá, C., Torrens, M., Ventura, M., Pujadas, M., ... & González, D. (2018). Acute Pharmacological Effects of 2C-B in Humans: An Observational Study. Frontiers in Pharmacology, 9, 206. https://doi.org/10.3389/fphar.2018.00206 Similarly, in the Shulgins’ book PiHKAL, pleasant experiences are described in the 16 to 24 mg range, but harrowing and more challenging trips were occasioned by higher doses, such as this trip report authored by someone who took a 64 mg dose: The first part of the book is Dr. Shulgin's own personal story as well as that of his wife and their friends and colleagues who helped out in the experimentation with phenethylamines. I'm not sure exactly how much is attributable to artistic license and how much is truthful. I believe it's "officially" fictional. Self incrimination and all... A beast-survivor takes shape in a child when the child feels that not only his behavior is bad but that he is bad. His repressed feelings assume the shape of a thing in his unconscious. If hes Christian, his shadow may assume the form of a devil. He will deny he has those feelings. Spiritual growth involves a confrontation with the beast-survivor.

In 1994, two years after PIHKAL was published, the Drug Enforcement Administration (DEA) raided Shulgin's lab and requested that he turn over his DEA license. Richard Meyer, spokesman for DEA's San Francisco Field Division, has stated in reference to PIHKAL "It is our opinion that those books are pretty much cookbooks on how to make illegal drugs. Agents tell me that in clandestine labs that they have raided, they have found copies of those books," suggesting that the publication of PIHKAL and the termination of Shulgin's license may have been related. [1] Notable compounds [ edit ] Essential amphetamines [ edit ]

As literature PIHKAL and TIHKAL are unusual for their hybridity. Some of the best postwar writing has been that which has managed to span the chasm between art and science, as in Primo Levi's The Periodic Table. The Shulgins' two big books span autobiography, organic chemistry, politics, ethnobotany and psychopharmacology. Their cultural impact is likely to be profound in the coming decades. A minor flaw is that while both books have an index for chemical compounds, neither has a general index: an oversight, especially given their great length. I'll sign off this review with a transcript of the picture above, because I know that sometimes food is best eaten pure.

Cannabis - Cannabis majorly intensifies and extends both the sensory and cognitive effects of 2C-B. Extreme caution should be exercised with this combination as it can also elevate the anxiety, confusion and psychosis risk of cannabis. Users have reported experiencing hypertension, hyperthermia and tachycardia at higher doses. [19] As such, those with pre-existing heart conditions should avoid using 2C-B, and users monitor their temperature and heart-rate and respond accordingly. Heavy physical exertion while on 2C-B is discouraged.

#142 PEA

so basically, this is a book by a chemist who has devoted his career to making and exploring psychedelics. what if you take the mescaline molecule and swap out this atom on the benzene ring? etc. etc. etc. each permutation basically gives rise to a cascade of other permutations. being that animal studies are useless for determining what psychedelic effects a human might experience from this or that chemical, he tries the compounds himself, going from a low dose upwards. if he detects a psychedelic effect and it doesn't seem terribly toxic, he then has a group of friends who take them as well and describe their experiences. the first part of the book is supposedly a novelization (presumably to provide plausible deniability in case any law enforcement agencies wanted to come after him), first in his voice, of his career as a psychedelic chemist, then in his second wife's voice, of her experience meeting him and joining him in testing his creations.